Well-designed medical research projects have been conducted by major universities, such as studies that provide substantial clinical proof that Type II Collagen may offer tremendous benefits to the millions of Americans suffering from debilitating joint problems.

Better yet, scientists are finding that when Collagen II is combined with specific minerals, fatty acids, vitamins, enzymes, and herbs, a powerful synergy occurs that can stop redness, swelling, and joint destruction. Even more, stiffness virtually disappears, allowing your connective tissues and vital supporting structure to heal and rebuild your joints.

Affecting one out of seven people, over 100 different types of bone/joint problems are lumped together under the term "arthritis." Unfortunately, current approaches are inadequate because they have unacceptable side effects. Anti-inflammatory agents (such as aspirin, naproxen, ibuprofen, and steroids) tear up your digestive, nervous, and immune systems while offering minimal, transient relief from bone/joint agony.

Research projects on Type II Collagen, which is derived from the breastbone of six-to-eight week-old chickens, are exploding onto the scientific scene. Type II Collagen first gained recognition from the prestigious Harvard University School of Medicine, but now many elite universities are broadening our understanding of exactly how this substance produces its phenomenal results.

Joint cartilage, tendons, and bones contain Type II Collagen as their most abundant structural protein. Although it has been known for years that Type II Collagen contains the most important compounds for connective tissue repair and production of new cartilage, little attention was focused on its life-enhancing potential until recently.

In fact, Brandeis University researchers teamed up with Boston University to conduct a groundbreaking study of primates that were artificially induced with arthritis. The monkeys given Type II Collagen injections did not experience joint problems, whereas all the others developed deformities and joint problems (Cathcart 1986).

Significant Improvement in Swelling and Tenderness
Inspired by this initial research, teams of researchers from Beth Israel Hospital, Brigham Young University, Women's Hospital and Harvard University produced the first wave of human studies that rocked the scientific world. The most challenging project utilized Type II Collagen of a placebo with 60 participants who had "severe rheumatoid arthritis." After three months, those receiving Type II Collagen experienced a highly significant improvement in swelling, tenderness, morning stiffness, grip strength, and walking ability. Four people went into complete remission, stunning the researchers (Trentham 1993).

Dr. Martha Barnett of Beth Israel Hospital Research Center formed research alliances with Duke University and the University of California to conduct a multi-center, double-blind study with 274 people at six different sites. They received either Type II Collagen or a placebo for six months at varying dosages. Type II Collagen was found to work in low doses to bring relief of bone/joint problems. The doctors marveled at its simplicity and excellent safety profile (Barnett 1998).

Noteworthy in all the recent research data is the fact that Type II Collagen does a lot more than alleviate misery, swelling and the immobilizing stiffness associated with joint problems. Type II Collagen has been found to contain naturally occurring Glucosamine Sulfate and Chondroitin Sulfate, nature's best known substances for restoring joints to health.

Whenever your joints have been damaged by immune system problems or by the "wear and tear" of aging, this well-tolerated nutrient enables your body to build a strong, new structural support. This restorative capacity puts Type II Collagen light-years ahead of compounds that simply address the symptoms of joint problems.

MSM Rebuilds Structural Integrity of Joints
To a significant degree, Vitamin C enhances the absorption of Type II Collagen within the cell structures of joint cartilage. Far more surprising, however, is that nature's richest source of sulfur, methylsulfonyl-methane (MSM); is extraordinarily helpful in regaining flexibility. Most Americans are deficient in this critically important mineral because MSM is lost when food is processed, cooked or stored.

Dr. Stanley Jacob (1967), a dedicated medical researcher at Oregon Health Sciences Institute, has devoted over 30 years to the study of MSM. His research efforts, as well as projects conducted globally, provide solid evidence of the power of MSM to perform important tasks related to joint problems. To begin with, MSM contributes to the production of "good substance," which keeps connective tissue intact.

Moreover, MSM enhances the structural integrity of mucopolysaccharides, found in high concentration in joint cartilage. Clinical evidence demonstrates significant relief from joint agony and stiffness (Ley 1998).

In fact, a study comparing effects of MSM and those of the nonsteroidal anti-inflammatory drug (NSAID) Motrin showed that both substances provided equal improvements in discomfort and stiffness after one month. However, NSAIDs can have dangerous side effects over the long term and do nothing to build cartilage like MSM does. Studies show that MSM makes cells permeable by regulating the sodium-potassium pump to allow fluids and nutrients to flow freely through the cell wall, thus removing toxins and nourishing the cells to promote healing (Ley 1998).

Extraordinary Enzyme
Current scientific evidence also suggests that Bromelain, a powerful enzyme, acts to control redness and swelling. Bromelain restores the healthy balance of prostaglandins without any of the unpleasant consequences of aspirin-type drugs, and it is more desirable for those suffering from the sharp burning or aching feeling associated with joint swelling (Taussig 1980).

While this extraordinary enzyme has been examined in hundreds of studies over the last 20 years, one sterling example leaps out from the literature. Over a five-year period, doctors administered Bromelain in their clinical practice to over 700 people suffering from joint redness and swelling, strains, contusions, abrasions and the like.

The doctors found that administration of Bromelain was usually followed by a marked subsidence of discomfort from swelling, with increased mobility. Further, the time between admission and discharge of patients was reduced by 35-50%. At least 80% of the people who took Bromelain obtained an excellent to good response. The clinicians agreed that few other enzymes "have such scope of action" (Taussig 1975).

Glucosamine/Chondroitin
When clinically evaluated for efficacy in the treatment of joint problems, Glucosamine & Chondroitin Sulfates have reportedly delivered significant benefits in facilitating the body's manufacturing of Collagen and Proteoglycans necessary for the restoration of healthy articular cartilage.

In this most exciting decade of breakthroughs in medical research, the arrival of these amazing nutrients ranks extremely high in terms of relief for so many millions with joint problems. When combined together, Type II Collagen, MSM, Glucosamine/Chondroitin and Bromelain provide you with powerful joint support. Say goodbye to the grueling agony and life-limiting signs of cartilage breakdown so you can get back to living again.

References:
· Barnett, M. et al. (1998). "Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter double-blind placebo controlled trial "Arthritis and Rheumatism"; 41(2):190-7.
· Cathcart, E. et al. (1986). "Experimental arthritis in a nonhuman primate. I. Introduction by bovine type II collagen." Laboratory Investigations; 54(1):26-31.
· Jacob, S.W. et al. (1967). "Dimethyl sulfoxide (DMSO). Toxicology, pharmacology, and clinical experience." American Journal of Surgery; 114(3):414-26.
· Ley, B. (1998). MSM: On Our Way Back to Health With Sulfur! Aliso Viejo, CA: BL Publications.
· Taussig, S. et al. (1975). "Bromelain: A proleolytic enzyme and its clinical application. A review. "Hiroshima Journal of Medical Sciences; 24(2-3): 186-93
· Taussig, S. (1980). "The mechanism of the physiological action of bromelain," Medical Hypothesis; 6(1):99-104.
· Trentham, D. et al. (1993). "Effects of oral administration of type II collagen on rheumatoid arthritis." Science; 261(51290;1727-30).

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