A nutritional supplement that is receiving increasingly greater media exposure and consumer interest with respect to joint health is Glucosamine Sulfate. Glucosamine is one of the major building blocks for the body's natural synthesis of the critical lubricants and shock absorbers necessary to restore and maintain healthy joint performance. Glucosamine is a precursor to the generation of glycosaminologycans and makes up 50% of the composition of hyaluronic acid, the natural lubricant found in synovial fluid. Both of these products are key components in the biosynthesis of collagen and the very large, shock absorbing molecules called proteoglycans that are integral constituents of the cartilage matrix. By supplementing the Glucosamine naturally present, the body is able to facilitate the manufacture of collagen and proteoglycans necessary for the restoration of healthy articular cartilage in injured joints and for the resupply of lubricant in the synovial fluid. When clinically evaluated for efficacy in the treatment of joint problems, Glucosamine has reportedly delivered the following results: - Significantly out-preformed ibuprofen with respect to reduction in patients suffering from knee joint problems. - Rated "Good" or "Sufficient" in 95% of 1,208 patients evaluated with respect to the therapeutic efficacy in the management of arthrosis. - Accelerated recovery and partially restored articular function of the knee. - Significantly relived symptoms (joint tenderness and restricted movement). - Almost double the speed and magnitude of improvement in articular function of the knee. - Chondroitin sulfates are integral components of all connective tissues, especially cartilage of joints and blood vessels. - Chondroitin sulfates give cartilage its resilience and cushioning properties by binding water. - Purified chondroitin sulfates are absorbed into the bloodstream in humans after oral ingestion, and are retained by connective tissues.

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